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Which of the following cell types is responsible for breaking down bone matrix?


A) osteoclast
B) fibroblast
C) osteocyte
D) chondroclast
E) chondroblast

F) B) and E)
G) A) and D)

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Which of the following is correctly matched?


A) short bone - carpal bone
B) long bone - vertebra
C) short bone - humerus
D) flat bone - phalanges of the toes
E) irregular bone - femur

F) None of the above
G) D) and E)

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The connective tissue sheath of cartilage is called the


A) ligamentous cord.
B) lacuna.
C) chondrocyte.
D) matrix.
E) perichondrium.

F) A) and C)
G) C) and D)

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A bone fracture generally found in children that is incomplete is a(an)


A) complicated fracture.
B) greenstick fracture.
C) dentate fracture.
D) hairline fracture.
E) spiral fracture.

F) A) and D)
G) A) and C)

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Sally has elevated levels of blood calcium.What chemical would you expect to find in high levels in response to this condition?


A) sex hormones
B) parathyroid hormone
C) growth hormone
D) calcitonin
E) vitamin D

F) B) and C)
G) A) and D)

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The spaces between developing skull bones that have not ossified are called


A) epiphyseal plates.
B) bone collars.
C) articular cartilages.
D) fontanels.
E) medullary cavities.

F) None of the above
G) A) and D)

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Which type of bone cells give rise to osteoblasts?


A) osteochondral progenitor cell
B) osteoblasts
C) osteoclasts
D) osteocytes

E) A) and C)
F) None of the above

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These are blood vessels that carry blood from the medullary cavity and periosteum to the osteon and run perpendicular to the long axis of the bone.


A) Haversian canals
B) lamellar canals
C) Volkmann canals
D) osteochondral canals
E) Sharpey's canals

F) A) and E)
G) B) and D)

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The sequence of events that produces growth at the epiphyseal plate is


A) hypertrophy,proliferation,calcification,ossification,and remodeling.
B) hypertrophy,calcification,proliferation,cell death,ossification,and remodeling.
C) proliferation,hypertrophy,calcification,cell death,ossification,and remodeling.
D) calcification,hypertrophy,proliferation,ossification,cell death,and remodeling.
E) proliferation,hypertrophy,cell death,calcification,ossification,and remodeling.

F) A) and E)
G) A) and D)

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Which of the following statements about bone growth is TRUE?


A) Most growth in long bones results from interstitial growth.
B) In the epiphyseal plate,osteoblasts degenerate to form chondrocytes.
C) Endochondral growth in long bones occurs at the epiphyseal plate.
D) Bones can not grow by appositional growth.
E) Appositional bone growth results in increased bone length.

F) B) and E)
G) A) and B)

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Osteoporosis is


A) bone inflammation that often results from bacterial infection.
B) a disease in adults characterized by softening of bones resulting from calcium depletion.
C) a group of genetic disorders producing very brittle bones that are easily fractured; occurs because of insufficient collagen development.
D) a disease in adults,especially women,characterized by a reduced amount of bone matrix.
E) a disease in children characterized by soft,bowed,and swollen bones.

F) A) and C)
G) A) and E)

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The zygomatic bone is an example of a(n)


A) long bone.
B) flat bone.
C) short bone.
D) irregular bone.

E) A) and D)
F) All of the above

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Calcitonin


A) decreases osteoblast activity.
B) is associated with decreased osteoclast activity.
C) decreases osteochondral progenitor cell activity.
D) decreases osteocyte activity.
E) has no effect on bone cells.

F) A) and B)
G) A) and C)

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The type of lamellae found between osteons (Haversian systems) is


A) interstitial.
B) oppositional.
C) appositional.
D) circumferential.
E) concentric.

F) B) and D)
G) A) and E)

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Appositional growth deposits a new layer of bone


A) in the epiphyseal plate of long bones.
B) in the secondary ossification center of the epiphyses.
C) on the surface of the bone.
D) on cancellous,but not compact bone.
E) in interstitial areas.

F) A) and C)
G) C) and D)

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In which type of bone are osteoblasts and osteoclasts present?


A) spongy bone
B) compact bone
C) both spongy and compact

D) All of the above
E) B) and C)

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Woven bone


A) has a porous appearance.
B) is not easily restructured.
C) has its collagen fibers randomly oriented.
D) is organized into thin sheets of tissue.
E) is very light in weight.

F) B) and E)
G) A) and E)

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True or false: Bone remodeling stops during puberty.

A) True
B) False

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The stem cells of osteoblasts and chondroblasts are


A) monocytes.
B) chondrocytes.
C) osteocytes.
D) osteoclasts.
E) osteochondral progenitor cells.

F) A) and E)
G) B) and E)

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The compression (weight-bearing) strength of bone matrix is due to the presence of


A) hydroxyapatite crystals.
B) collagenase.
C) collagen fibers.
D) elastin fibers.
E) bone marrow.

F) A) and E)
G) A) and D)

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