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Which of the following would reduce the glomerular filtration rate?


A) vasoconstriction of the efferent arteriole
B) a drop in oncotic pressure
C) vasodilation of the afferent arteriole
D) vasoconstriction of the afferent arteriole
E) an increase in osmotic pressure in the glomerular capsule

F) A) and B)
G) A) and C)

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Which of these correctly traces blood flow from the renal artery into the renal cortex?


A) arcuate a.→ interlobar a.→ afferent arteriole → interlobular a.
B) interlobar a.→ interlobular a.→ segmental a.→ arcuate a.
C) segmental a.→ interlobar a.→ arcuate a.→ interlobular a.
D) afferent arteriole → interlobular a.→ arcuate a.→ interlobar a.
E) segmental a.→ arcuate a.→ interlobar a.→ interlobular a.

F) B) and D)
G) C) and D)

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Which two substances are most useful for determining a patient's glomerular filtration rate?


A) insulin and glucose
B) inulin and creatinine
C) sodium and water
D) albumin and inulin
E) insulin and urea

F) A) and E)
G) B) and E)

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All of the following are composed of cuboidal epithelium with the exception of


A) the thin segment of the nephron loop.
B) the thick segment of the nephron loop.
C) the collecting duct.
D) the proximal convoluted tubule.
E) the distal convoluted tubule.

F) B) and D)
G) A) and C)

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Assuming all other values are normal, calculate the net filtration pressure in a patient with a drop in capsular hydrostatic pressure to 8 mmHg.


A) 10 mm Hg out
B) 20 mm Hg out
C) 30 mm Hg out
D) 40 mm Hg out
E) 50 mm Hg out

F) A) and B)
G) A) and C)

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Angiotensin-converting enzyme is found only in the kidneys and converts angiotensinogen to angiotensin I.

A) True
B) False

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The transition from an afferent arteriole to an efferent arteriole occurs in the


A) glomerulus.
B) medulla.
C) cortical radiate veins.
D) peritubular capillaries.
E) vasa recta.

F) All of the above
G) A) and B)

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The ureters pass anterior to the bladder and enter it from below.

A) True
B) False

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The countercurrent multiplier recaptures and is based on fluid flowing in direction in two adjacent tubules.


A) potassium; the same
B) calcium; the opposite
C) calcium; the same
D) sodium; the opposite
E) sodium; the same

F) A) and B)
G) B) and D)

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Total saturation of protein transporters for a given solute in the renal tubules would result in


A) reabsorption of all the solute.
B) a renal clearance of zero.
C) a net filtration pressure of 1.0.
D) appearance of that solute in the urine.
E) absence of that solute from the urine.

F) B) and E)
G) A) and B)

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The urine is most likely to be hypotonic when


A) the body's water volume is high.
B) the body's pH is low.
C) the output of antidiuretic hormone is high.
D) the output of natriuretic peptides is high.
E) a person is lost and deprived of drinking water.

F) D) and E)
G) A) and D)

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Cells in the cleft between the afferent and efferent arterioles and among capillaries of the glomerulus are known as mesangial cells.

A) True
B) False

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In the nephron, the fluid that immediately precedes urine is known as


A) plasma.
B) glomerular filtrate.
C) tubular fluid.
D) renal filtrate.
E) medullary filtrate.

F) A) and E)
G) A) and D)

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Which organ system does not excrete waste?


A) the urinary system
B) the cardiovascular system
C) the integumentary system
D) the digestive system
E) the respiratory system

F) C) and D)
G) A) and B)

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Which of the following is a direct result of antidiuretic hormone?


A) decreased urine volume
B) decreased urine molarity
C) increased urine volume
D) increased urine salinity
E) increased urine acidity

F) C) and D)
G) A) and B)

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Which of the following is not found in the ureter?


A) adventitia
B) two layers of smooth muscle
C) three layers of smooth muscle
D) transitional epithelium
E) skeletal muscle

F) C) and D)
G) B) and C)

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The thick segment of the nephron loop is impermeable to water.

A) True
B) False

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The fenestrated endothelium of the capillary has pores small enough to exclude blood cells from the filtrate.

A) True
B) False

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Which is not a portion of the urethra?


A) external urethral orifice
B) internal urethral sphincter
C) prostatic urethra
D) membranous urethra
E) spongy urethra

F) B) and D)
G) All of the above

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A hospital patient produces 4 mL/min of urine with a urea concentration of 8 mg/mL.Venous blood draw reveals urea concentration of 0.4 mg/mL.What is the percentage of cleared urea from glomerular filtrate?


A) 40%
B) 56%
C) 64%
D) 72%
E) 80%

F) B) and E)
G) A) and B)

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