Question 1

What was one of the pieces of evidence most critical to the discovery of DNA structure?

Accepted Answer

A)  its composition of four different nucleotides
B)  its mode of replication
C)  an X-ray diffraction pattern suggesting a double helix shape
D)  the backbone containing sugar-phosphate linkages
E)  the covalent bonding between different nucleotidesF) B) and E)
G) A) and E)

Question 2

Without the work of Rosalind Franklin,Watson and Crick would not have known

Accepted Answer

A)  which nucleotides could pair together.
B)  how many strands of DNA made up the molecule.
C)  the shape of the molecule.
D)  the width of the molecule.
E)  nucleotide pairs,number of strands,molecular shape,and molecular width.F) All of the above
G) A) and B)

Question 3

All of these are critical factors for DNA replication on the leading strand EXCEPT

Accepted Answer

A)  primer
B)  DNA ligase
C)  DNA polymerase
D)  DNA primase
E)  deoxynucleoside triphosphatesF) A) and C)
G) A) and E) B

Question 4

Which statement about the structure or composition of DNA is FALSE?

Accepted Answer

A)  DNA is a double helix.
B)  Complementary base-pairing occurs between pyrimidine and purine bases.
C)  The amount of thymine closely approximates that of guanine within a particular organism.
D)  Each nucleotide within a DNA is separated by about 0.34 angstroms.
E)  Adenine pairs with thymine and guanine with cytosinE.F) A) and D)
G) B) and D) C

Question 5

A DNA specimen that contains 30% guanine contains how much thymine?

Accepted Answer

A)  15%
B)  20%
C)  30%
D)  60%
E)  The amount of thymine cannot be determined.F) A) and D)
G) C) and D)

Question 6

Which of these proteins-functions is mismatched?

Accepted Answer

A)  DNA polymerase..........DNA synthesis
B)  DNA polymerase..........primer removal and replacement with DNA
C)  DNA primase..........production of RNA primer
D)  topoisomerase..........separates double-stranded DNA into single strands
E)  single-stranded binding proteins..........prevents single DNA strands from reforming into a double helixF) C) and D)
G) A) and D)

Question 7

Which of these statements is FALSE?

Accepted Answer

A)  One chromosome is made up of many DNA molecules
B)  A eukaryotic genome is made up of many DNA molecules
C)  A DNA double helix is composed of both covalent bonds and hydrogen bonds
D)  A strand of DNA is made up of many nucleotidesE) None of the above
F) A) and C)

Question 8

Which characteristic of genetic material accounts for the phenomenon of natural selection?

Accepted Answer

A)  Information
B)  Replication
C)  Transmission
D)  Replication and Transmission
E)  VariationF) B) and C)
G) A) and B)

Question 9

How many replication forks are there at an origin of replication?

Accepted Answer

A)  1
B)  2
C)  3
D)  4
E)  5F) A) and B)
G) All of the above

Question 10

DNA helicase and topoisomerase are similar insofar as they promote the unwinding and uncoiling of DNA.

Accepted Answer

A) True 
 B)False

Question 11

A strand of DNA is composed of nucleotide bases,sulfate groups,and sugars.

Accepted Answer

A) True 
 B)False

Question 12

Which is not a pyrimidine?

Accepted Answer

A)  adenine
B)  thymine
C)  cytosine
D)  uracil
E)  cytosine and thymineF) A) and B)
G) D) and E) A

Question 13

What can be said about the leading versus the lagging strand in DNA population?

Accepted Answer

A)  The leading strand is replicated continuously for the entire length of the chromosome,while the lagging strand is replicated in pieces.
B)  The lagging strand is synthesized in a semiconservative fashion while the leading strand is synthesized in a conservative fashion
C)  Synthesis of the lagging strand requires more helicase enzymes than synthesis of the leading strand.
D)  The lagging strand has a higher mutation rate than the leading strandE) B) and D)
F) A) and B)

Question 14

Which characteristic of genetic material accounts for the need to get a flu vaccine every year,but a polio vaccine once in a life time?

Accepted Answer

A)  Information
B)  Replication
C)  Transmission
D)  Replication and Transmission
E)  VariationF) A) and C)
G) D) and E)

Question 15

Bacteria are grown in 15N (heavy) medium and then transferred to 14N (light) medium and are allowed to replicate for 1 generation.The DNA is subsequently isolated and centrifuged in a CsCl2 gradient to yield what type of gradient band(s) ?

Accepted Answer

A)  one heavy band
B)  one light band
C)  one half-heavy (intermediate to heavy and light) band
D)  one heavy and one half-heavy band
E)  one heavy and one light bandF) A) and B)
G) All of the above

Question 16

The nucleotides within DNA are composed of a

Accepted Answer

A)  phosphate group,ribose sugar,and nitrogenous base.
B)  sulfur group,ribose sugar,and nitrogenous base.
C)  phosphate group,deoxyribose sugar,and nitrogenous base.
D)  sulfur group,deoxyribose sugar,and nitrogenous base.
E)  phosphate group,hexose sugar,and nitrogenous basE.F) C) and E)
G) B) and D)

Question 17

What is the highest (or most complex) level of structure for genetic material?

Accepted Answer

A)  nucleotide
B)  double helix
C)  DNA
D)  gene
E)  chromosomeF) D) and E)
G) All of the above

Question 18

This produces short sequences of RNA,which allows polymerase to synthesize a new strand of DNA.

Accepted Answer

A)  DNA primase
B)  DNA helicase
C)  DNA polymerase
D)  DNA topoisomerase
E)  DNA ligaseF) B) and D)
G) B) and C)

Question 19

If there is 28% adenine,then there must be 28% cytosine for the DNA composition of a particular organism.

Accepted Answer

A) True 
 B)False

Question 20

In order to produce a single strand of DNA the nucleotides combine to form what type of bond?

Accepted Answer

A)  hydrogen
B)  peptide
C)  phosphodiester
D)  purine
E)  ionicF) A) and C)
G) C) and D)

Exam 9: Nucleic Acid Structure, DNA Replication, and Chromosome Structure

What was one of the pieces of evidence most critical to the discovery of DNA structure?

Correct AnswerverifiedShow Answer

Without the work of Rosalind Franklin,Watson and Crick would not have known

Correct AnswerverifiedShow Answer

All of these are critical factors for DNA replication on the leading strand EXCEPT

Correct AnswerverifiedB

Which statement about the structure or composition of DNA is FALSE?

Correct AnswerverifiedC

A DNA specimen that contains 30% guanine contains how much thymine?

Correct AnswerverifiedShow Answer

Which of these proteins-functions is mismatched?

Correct AnswerverifiedShow Answer

Which of these statements is FALSE?

Correct AnswerverifiedShow Answer

Which characteristic of genetic material accounts for the phenomenon of natural selection?

Correct AnswerverifiedShow Answer

How many replication forks are there at an origin of replication?

Correct AnswerverifiedShow Answer

DNA helicase and topoisomerase are similar insofar as they promote the unwinding and uncoiling of DNA.

Correct AnswerverifiedShow Answer

A strand of DNA is composed of nucleotide bases,sulfate groups,and sugars.

Correct AnswerverifiedShow Answer

Which is not a pyrimidine?

Correct AnswerverifiedA

What can be said about the leading versus the lagging strand in DNA population?

Correct AnswerverifiedShow Answer

Which characteristic of genetic material accounts for the need to get a flu vaccine every year,but a polio vaccine once in a life time?

Correct AnswerverifiedShow Answer

Bacteria are grown in 15N (heavy) medium and then transferred to 14N (light) medium and are allowed to replicate for 1 generation.The DNA is subsequently isolated and centrifuged in a CsCl2 gradient to yield what type of gradient band(s) ?

Correct AnswerverifiedShow Answer

The nucleotides within DNA are composed of a

Correct AnswerverifiedShow Answer

What is the highest (or most complex) level of structure for genetic material?

Correct AnswerverifiedShow Answer

This produces short sequences of RNA,which allows polymerase to synthesize a new strand of DNA.

Correct AnswerverifiedShow Answer

If there is 28% adenine,then there must be 28% cytosine for the DNA composition of a particular organism.

Correct AnswerverifiedShow Answer

In order to produce a single strand of DNA the nucleotides combine to form what type of bond?

Correct AnswerverifiedShow Answer

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B

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C

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A

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Bacteria are grown in ¹⁵N (heavy) medium and then transferred to ¹⁴N (light) medium and are allowed to replicate for 1 generation.The DNA is subsequently isolated and centrifuged in a CsCl₂ gradient to yield what type of gradient band(s) ?

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