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Metabotropic synapses use a large variety of transmitters.

A) True
B) False

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What does it mean to say that acetylcholine exerts ionotropic effects?


A) It opens gates for a particular ion.
B) It alters the permeability of the presynaptic neuron.
C) It increases the concentration of ions within the vesicles.
D) It changes the electrical charge of sodium ions from positive to negative.

E) A) and B)
F) B) and D)

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Which of the following statements regarding reflexes would Charles Sherrington most likely agree with?


A) The overall speed of conduction through a reflex arc is faster than conduction along an axon.
B) Repeated stimuli occurring within a brief time can have a cumulative effect.
C) Each neuron physically merges with the next one.
D) Excitatory synapses are more important than inhibitory synapses.

E) A) and D)
F) None of the above

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The presynaptic terminal stores high concentrations of neurotransmitter molecules in:


A) axons
B) vesicles
C) peptides
D) dendrites

E) A) and B)
F) B) and C)

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What determines whether a neuron has an action potential?


A) only the number of EPSPs impinging on an axon
B) only the number of IPSPs impinging on the dendrites
C) the combined effects of EPSPs and IPSPs
D) summation effects of IPSPs

E) None of the above
F) A) and B)

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A drug that blocks the effects of a neurotransmitter is a(n) ____; a drug that mimics or increases the effects is a(n) ____.


A) neuromodulator; synergist
B) agonist; antagonist
C) depressant; stimulant
D) antagonist; agonist

E) A) and B)
F) A) and C)

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Simultaneous weak stimuli at different locations produce a greater reflexive response than one of the stimuli by itself. What is this phenomenon called?


A) Sherrington's law
B) temporal summation
C) spatial summation
D) the all-or-none law

E) None of the above
F) A) and B)

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After serotonin or one of the catecholamine transmitters stimulates the postsynaptic receptor, most of the transmitter molecules:


A) remain on the receptor until other neurotransmitters replace them.
B) are broken into components while still attached to the postsynaptic cell.
C) are metabolized by the postsynaptic cell as a source of energy.
D) are reabsorbed by the presynaptic cell.

E) A) and B)
F) All of the above

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Most habit-forming drugs activate which type of synapse?


A) acetylcholine
B) opiate
C) GABA
D) dopamine

E) A) and B)
F) A) and C)

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What determines the effect that a neurotransmitter has on the postsynaptic neuron?


A) the speed the action potential traveled down the axon
B) the number of branches of the presynaptic axon
C) the receptors on the postsynaptic membrane
D) the distance between the synapse and the cell body

E) B) and C)
F) None of the above

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At synapses, the cell that receives the message is called the presynaptic neuron.

A) True
B) False

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List the major types of neurotransmitters.

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Amino acids, neurope...

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The tiny packets that contain neurotransmitters in the presynaptic neuron are called:


A) vesicles.
B) bags.
C) sacs.
D) terminals.

E) A) and C)
F) None of the above

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Exocytosis is the process by which neurotransmitters are:


A) excreted into the synaptic cleft.
B) synthesized.
C) destroyed.
D) secreted into synaptic vesicles.

E) A) and B)
F) All of the above

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Inhibitory synapses on a neuron:


A) hyperpolarize the postsynaptic cell.
B) weaken the cell's polarization.
C) increase the probability of an action potential.
D) move the potential closer to the cell's threshold.

E) None of the above
F) A) and B)

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The neuron excretes neurotransmitter through its membrane by a process called:


A) Dale's principle.
B) exocytosis.
C) endocytosis.
D) voltage-dependent flow.

E) A) and B)
F) None of the above

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Only sensory neurons are found in a reflex arc.

A) True
B) False

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The main advantage of a neuron releasing more than one neurotransmitter is that:


A) if it runs out of one, it has others.
B) it can release different transmitters on different occasions.
C) it can send more complex messages.
D) it can release one from the axon's terminal and one from another location along the axon.

E) A) and B)
F) B) and C)

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At the synapse, amphetamine:


A) blocks the breakdown of dopamine.
B) decreases the release of dopamine from the presynaptic terminal.
C) inhibits the dopamine transporter.
D) decreases the sensitivity of dopamine receptors.

E) B) and C)
F) A) and D)

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On the basis of what evidence were the properties of synapses first inferred?


A) the electron microscope
B) single-neuron recordings
C) behavioral observations
D) PET scans

E) All of the above
F) C) and D)

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